7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6781 | Benzenesulfonamide | Benzenesulphonamide,Phenyl sulfonamide,Benzosulfonamide | Carbonic Anhydrase |
Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases. | |||
T2134 | Dorzolamide hydrochloride | MK507 hydrochloride,L671152 hydrochloride,MK-507 (L-671152) HCl,Dorzolamide HCl | Carbonic Anhydrase |
Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water ... | |||
T0782 | Benzthiazide | Aquatag,Lemazide,Dihydrex | Carbonic Anhydrase |
Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted ... | |||
T61829 | Carbonic anhydrase inhibitor 4 | ||
Carbonic anhydrase inhibitor 4 is a photoprobe that inhibits the activity of carbonic anhydrase. It specifically targets human carbonic anhydrases, including hCA I-XIV, with K i values ranging from 640-1166 nM [1]. | |||
T35713 | N-desethyl Brinzolamide (oxalate) | ||
N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively). 1.Kim, C.-Y., Whittington, D.A., Chang... | |||
T79753 | HCAIX/XII-IN-8 | Carbonic Anhydrase | |
hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.7 nM for CA XII. It demonstrates significant inhibitory effi... | |||
T79591 | HCA/VEGFR-2-IN-4 | VEGFR | |
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/XII and vascular endothelial growth factor receptor 2 (VEGFR... |